Caloric restriction enhances inheritance of wild-type mitochondrial DNA in Saccharomyces cerevisiae
Abstract In Saccharomyces cerevisiae, an asymmetrical division model, mitochondrial (mt) DNA typically exists in a homoplasmic state, but mutations frequently occur. Rolling-circle replication, mediated by the mtDNA recombinase Mhr1p, forms tandem concatemers that are selectively transmitted to budd...
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| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
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Nature Portfolio
2025-11-01
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| Σειρά: | Scientific Reports |
| Θέματα: | |
| Διαθέσιμο Online: | https://doi.org/10.1038/s41598-025-23888-x |
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