MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect

Abstract Multiplex assays of variant effect (MAVEs), such as deep mutational scans and massively parallel reporter assays, test thousands of sequence variants in a single experiment. Despite the importance of MAVE data for basic and clinical research, there is no standard resource for their discover...

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書誌詳細

主要な著者:	Daniel Esposito, Jochen Weile, Jay Shendure, Lea M. Starita, Anthony T. Papenfuss, Frederick P. Roth, Douglas M. Fowler, Alan F. Rubin
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2019-11-01
シリーズ:	Genome Biology
主題:	Deep mutational scanning Massively parallel reporter assays Large-scale mutagenesis MAVE Multiplexed assay of variant effect Genome interpretation
オンライン･アクセス:	http://link.springer.com/article/10.1186/s13059-019-1845-6
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