Effect of microbubble-assisted gemcitabine delivery with repeated ultrasound exposure in a pancreatic cancer organ-on-a-chip model
Abstract The fibrotic stroma of solid tumours poses a physical barrier to drug delivery and effective treatment. Interaction between cancerous epithelial cells and their surrounding stromal partners results in the development of a rigid, collagenous matrix environment with reduced interstitial flow,...
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| Автори: | , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Portfolio
2025-12-01
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| Серія: | Scientific Reports |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1038/s41598-025-30612-2 |
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