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The Na+, K+-ATPase β1 subunit regulates epithelial tight junctions via MRCKα

An intact lung epithelial barrier is essential for lung homeostasis. The Na+, K+-ATPase (NKA), primarily serving as an ion transporter, also regulates epithelial barrier function via modulation of tight junctions. However, the underlying mechanism is not well understood. Here, we show that overexpre...

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Principais autores: Haiqing Bai, Rui Zhou, Michael Barravecchia, Rosemary Norman, Alan Friedman, Deborah Yu, Xin Lin, Jennifer L. Young, David A. Dean
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical investigation 2021-02-01
Serier:JCI Insight
Fag:
Cell biology
Pulmonology
Online adgang:https://doi.org/10.1172/jci.insight.134881
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