YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB
The ubiquitin ligase TRAF6 is a key regulator of canonical IκB kinase (IKK)/NF-κB signaling in response to interleukin-1 (IL-1) stimulation. Here, we identified the deubiquitinating enzyme YOD1 (OTUD2) as a novel interactor of TRAF6 in human cells. YOD1 binds to the C-terminal TRAF homology domain o...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
eLife Sciences Publications Ltd
2017-02-01
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| Saila: | eLife |
| Gaiak: | |
| Sarrera elektronikoa: | https://elifesciences.org/articles/22416 |
| Etiketak: |
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