क्यूआर कोड

Virtual Screening, Molecular Dynamics, and Mechanism Study of Homeodomain-Interacting Protein Kinase 2 Inhibitor in Renal Fibroblasts

<b>Background/Objectives:</b> Homeodomain-interacting protein kinase 2 (HIPK2) is critically involved in the progression of renal fibrosis. This study aims to identify and characterize a novel HIPK2 inhibitor, CHR-6494, and investigate its therapeutic potential. <b>Methods:</b> Using structure-based...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Xinlan Hu, Yan Wu, Hanyi Ouyang, Jiayan Wu, Mengmeng Yao, Zhuo Chen, Qianbin Li
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2024-10-01
श्रृंखला:Pharmaceuticals
विषय:
renal fibrosis
HIPK2
kinase inhibitor
SIAH2
degradation
ऑनलाइन पहुंच:https://www.mdpi.com/1424-8247/17/11/1420
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