Virtual Screening, Molecular Dynamics, and Mechanism Study of Homeodomain-Interacting Protein Kinase 2 Inhibitor in Renal Fibroblasts
<b>Background/Objectives:</b> Homeodomain-interacting protein kinase 2 (HIPK2) is critically involved in the progression of renal fibrosis. This study aims to identify and characterize a novel HIPK2 inhibitor, CHR-6494, and investigate its therapeutic potential. <b>Methods:</b> Using structure-based...
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| Автори: | , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
MDPI AG
2024-10-01
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| Серія: | Pharmaceuticals |
| Предмети: | |
| Онлайн доступ: | https://www.mdpi.com/1424-8247/17/11/1420 |
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