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HIPK4 is essential for murine spermiogenesis

Mammalian spermiogenesis is a remarkable cellular transformation, during which round spermatids elongate into chromatin-condensed spermatozoa. The signaling pathways that coordinate this process are not well understood, and we demonstrate here that homeodomain-interacting protein kinase 4 (HIPK4) is...

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Autori principali: J Aaron Crapster, Paul G Rack, Zane J Hellmann, Austen D Le, Christopher M Adams, Ryan D Leib, Joshua E Elias, John Perrino, Barry Behr, Yanfeng Li, Jennifer Lin, Hong Zeng, James K Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2020-03-01
Serie:eLife
Soggetti:
spermiogenesis
cytoskeleton
fertility
HIPK4
kinase
Accesso online:https://elifesciences.org/articles/50209
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