The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma

Abstract Background Synthetic indolyl- pyridinyl- propenones (IPPs) induce methuosis, a form of non-apoptotic cell death, in glioblastoma and other cancer cell lines. Methuosis is characterized by accumulation of cytoplasmic vacuoles derived from macropinosomes and late endosomes, followed by metabo...

Descrición completa

Detalles Bibliográficos

Principais autores:	Zehui Li, Nneka E. Mbah, Jean H. Overmeyer, Jeffrey G. Sarver, Sage George, Christopher J. Trabbic, Paul W. Erhardt, William A. Maltese
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2019-01-01
Series:	BMC Cancer
Assuntos:	Glioblastoma Methuosis Cell death Chalcones C-Jun N-terminal kinase Vacuoles
Acceso en liña:	http://link.springer.com/article/10.1186/s12885-019-5288-y
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!