The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma

Abstract Background Synthetic indolyl- pyridinyl- propenones (IPPs) induce methuosis, a form of non-apoptotic cell death, in glioblastoma and other cancer cell lines. Methuosis is characterized by accumulation of cytoplasmic vacuoles derived from macropinosomes and late endosomes, followed by metabo...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Zehui Li, Nneka E. Mbah, Jean H. Overmeyer, Jeffrey G. Sarver, Sage George, Christopher J. Trabbic, Paul W. Erhardt, William A. Maltese
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2019-01-01
Serija:	BMC Cancer
Teme:	Glioblastoma Methuosis Cell death Chalcones C-Jun N-terminal kinase Vacuoles
Online dostop:	http://link.springer.com/article/10.1186/s12885-019-5288-y
Oznake:	Označite Brez oznak, prvi označite!