HSP90/PUS7/THUMPD1 promotes metastasis and cisplatin resistance in gastric cancer cells
Abstract The metastasis and chemotherapy resistance of gastric cancer significantly contribute to treatment failure and mortality. Based on previous studies, we hypothesized that Heat Shock Protein 90 (HSP90) interacts with and upregulates Pseudouridine Synthase 7 (PUS7), which in turn promotes THUM...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Nature Portfolio
2025-10-01
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| Schriftenreihe: | Scientific Reports |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1038/s41598-025-20167-7 |
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