M2 macrophage−derived exosomes improves secondary lymphedema through cellular mitochondrial homeostasis regulation via the Keap1-Nrf2/mPTP axis

BackgroundSecondary lymphedema leads to progressive tissue remodeling and immune dysregulation. Dysregulation of macrophage polarization critically influences pathological progression. Oxidative stress and mitochondrial homeostasis are the critical components of secondary lymphedema.MethodsA seconda...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Jinli Ma, Luya Pu, Yundong Zhang, Baiao Wu, Rui Fei, Dongmei Han, Miao Hao, Jianshi Du
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2026-07-01
Sarja:	Frontiers in Immunology
Aiheet:	exosome macrophage polarization mitochondrial permeability transition pore Nrf2 secondary lymphedema
Linkit:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1832261/full
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