Aerosolized nicotine-free e-liquid base constituents exacerbates mitochondrial dysfunction and endothelial glycocalyx shedding via the AKT/GSK3β-mPTP pathway in lung injury models

Abstract Smoking has been recognized as a risk factor of cancer, heart disease, stroke, diabetes, and lung diseases such as chronic obstructive pulmonary disease, and nicotine appears to be the responsible component of tobacco smoke that affects lung development. While nicotine-free electronic cigar...

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Auteurs principaux:	Ziyu Dai, Bin Xie, Chen Jiang, Yun Peng, Jianing Lin, Qiong Chen, Jingyi Sun
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2025-03-01
Collection:	Respiratory Research
Sujets:	Nicotine-free e-cigarette Cytotoxicity Mitochondrial dysfunction Endothelial glycocalyx AKT/GSK3β pathway mPTP opening
Accès en ligne:	https://doi.org/10.1186/s12931-025-03155-3
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