Improving TCR Gene Therapy for Treatment of Haematological Malignancies
Adoptive immunotherapy using TCR gene modified T cells may allow separation of beneficial Graft versus tumour responses from harmful GvHD. Improvements to this include methods to generate high avidity or high affinity TCR, improvements in vector design and reduction in mispairing. Following adoptive...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley
2012-01-01
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| Serier: | Advances in Hematology |
| Online adgang: | http://dx.doi.org/10.1155/2012/404081 |
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