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Improving TCR Gene Therapy for Treatment of Haematological Malignancies

Adoptive immunotherapy using TCR gene modified T cells may allow separation of beneficial Graft versus tumour responses from harmful GvHD. Improvements to this include methods to generate high avidity or high affinity TCR, improvements in vector design and reduction in mispairing. Following adoptive...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Emma Nicholson, Sara Ghorashian, Hans Stauss
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley 2012-01-01
Cyfres:Advances in Hematology
Mynediad Ar-lein:http://dx.doi.org/10.1155/2012/404081
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