Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils
Myeloid lineage cells suppress T cell viability through arginine depletion via arginase 1 (ARG1). Despite numerous studies exploring the mechanisms by which ARG1 perturbs lymphocyte function, the cellular populations responsible for its generation and release remain poorly understood. Here, we showe...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2022-11-01
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| Serie: | The Journal of Clinical Investigation |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1172/JCI153643 |
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