Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2

Abstract Bacterial sepsis results in high mortality rates, and new therapeutics to control infection are urgently needed. Here, we investigate the therapeutic potential of fibrates in the treatment of bacterial sepsis and examine their effects on innate immunity. Fibrates significantly improved the...

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Bibliografiska uppgifter

Huvudupphov:	Ivan Tancevski, Manfred Nairz, Kristina Duwensee, Kristina Auer, Andrea Schroll, Christiane Heim, Clemens Feistritzer, Julia Hoefer, Romana R Gerner, Alexander R Moschen, Ingrid Heller, Petra Pallweber, Xiaorong Li, Markus Theurl, Egon Demetz, Anna M Wolf, Dominik Wolf, Philipp Eller, Andreas Ritsch, Guenter Weiss
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Springer Nature 2014-04-01
Serie:	EMBO Molecular Medicine
Ämnen:	chemokine receptor fenofibrate infection inflammation neutrophils
Länkar:	https://doi.org/10.1002/emmm.201303415
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