Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils

Myeloid lineage cells suppress T cell viability through arginine depletion via arginase 1 (ARG1). Despite numerous studies exploring the mechanisms by which ARG1 perturbs lymphocyte function, the cellular populations responsible for its generation and release remain poorly understood. Here, we showe...

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Manylion Llyfryddiaeth

Prif Awduron:	Huajia Zhang, Xiaodong Zhu, Travis J. Friesen, Jeff W. Kwak, Tatyana Pisarenko, Surapat Mekvanich, Mark A. Velasco, Timothy W. Randolph, Julia Kargl, A. McGarry Houghton
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Clinical Investigation 2022-11-01
Cyfres:	The Journal of Clinical Investigation
Pynciau:	Immunology Oncology
Mynediad Ar-lein:	https://doi.org/10.1172/JCI153643
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