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Pegylated chitosan nanoparticles of fluoxetine enhance cognitive performance and hippocampal brain derived neurotrophic factor levels in a rat model of local demyelination

Cognitive impairment is a common feature in neurodegenerative diseases such as multiple sclerosis (MS). This study aims to explore the potential of enhancing the beneficial effects of fluoxetine (FLX), a neuroprotective agent known for its ability to increase neural plasticity by utilizing nanoparti...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Masoomeh Dadkhah, Salva Afshari, Tara Samizadegan, Leila Rezaie Shirmard, Sajjad Barin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-10-01
Schriftenreihe:Experimental Gerontology
Schlagworte:
Cognitive impairment
Demyelination
Lysophosphatidylcholine
Fluoxetine
IGF-1
BDNF
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S053155652400175X
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