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Pegylated chitosan nanoparticles of fluoxetine enhance cognitive performance and hippocampal brain derived neurotrophic factor levels in a rat model of local demyelination

Cognitive impairment is a common feature in neurodegenerative diseases such as multiple sclerosis (MS). This study aims to explore the potential of enhancing the beneficial effects of fluoxetine (FLX), a neuroprotective agent known for its ability to increase neural plasticity by utilizing nanoparti...

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Principais autores: Masoomeh Dadkhah, Salva Afshari, Tara Samizadegan, Leila Rezaie Shirmard, Sajjad Barin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-10-01
coleção:Experimental Gerontology
Assuntos:
Cognitive impairment
Demyelination
Lysophosphatidylcholine
Fluoxetine
IGF-1
BDNF
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S053155652400175X
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