Modulation of Apoptotic Cell Death and Neuroprotective Effects of Glutathione—L-Dopa Codrug Against H₂O₂-Induced Cellular Toxicity

The L-3,4-dihydroxyphenylalanine (LD) is the gold standard drug currently used to manage Parkinson’s disease (PD) and to control its symptoms. However, LD could cause disease neurotoxicity due to the generation of pro-oxidant intermediates deriving from its autoxidation. In order to overcome t...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Sara Franceschelli, Paola Lanuti, Alessio Ferrone, Daniela Maria Pia Gatta, Lorenza Speranza, Mirko Pesce, Alfredo Grilli, Ivana Cacciatore, Emanuela Ricciotti, Antonio Di Stefano, Sebastiano Miscia, Mario Felaco, Antonia Patruno
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2019-08-01
Rangatū:	Antioxidants
Ngā marau:	L-Dopa glutathione SH-SY5Y cell line U-937 cell line Parkinson’s disease ROS apoptosis
Urunga tuihono:	https://www.mdpi.com/2076-3921/8/8/319
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!