Effects of low intracellular glutathione and CbrA-CbrB-Crc signaling on methylglyoxal sensitivity in Pseudomonas aeruginosa LasR-deficient mutants
ABSTRACT Pseudomonas aeruginosa, which causes many types of infections, often has loss-of-function mutations in the gene encoding LasR, a transcription factor involved in quorum sensing. Here, we report that LasR− strains are more sensitive to the electrophile methylglyoxal (MGO), which is produced...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2025-10-01
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| Serie: | Journal of Bacteriology |
| Soggetti: | |
| Accesso online: | https://journals.asm.org/doi/10.1128/jb.00394-24 |
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