Effects of low intracellular glutathione and CbrA-CbrB-Crc signaling on methylglyoxal sensitivity in Pseudomonas aeruginosa LasR-deficient mutants

ABSTRACT Pseudomonas aeruginosa, which causes many types of infections, often has loss-of-function mutations in the gene encoding LasR, a transcription factor involved in quorum sensing. Here, we report that LasR− strains are more sensitive to the electrophile methylglyoxal (MGO), which is produced...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Ana Altamirano, Marina Ruzic, Anna E. Cryan, Deborah A. Hogan
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology 2025-10-01
Цуврал:	Journal of Bacteriology
Нөхцлүүд:	Pseudomonas aeruginosa methylglyoxal LasR CbrAB glutathione GloA3
Онлайн хандалт:	https://journals.asm.org/doi/10.1128/jb.00394-24
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!