Multi-omics analysis identifies gut microbiota-glutamine axis contributing to the pathogenesis of reflux esophagitis

BackgroundReflux esophagitis (RE), a common gastroesophageal reflux disease characterized by esophageal mucosal inflammation, is closely associated with gut microbiota dysbiosis and metabolic abnormalities. The glutamine-glutamate metabolic pathway regulates inflammation and mucosal barrier function...

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Podrobná bibliografie

Hlavní autoři:	Yu Wu, Qi Gao, Huichao Yang, Yu Wang, Lin Lang, Bin Liu, Xiaolin Jiang, Di Li, Ximo Wang, Jing Xun, Qi Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-05-01
Edice:	Frontiers in Microbiology
Témata:	glutamine glutamine-glutamate metabolic pathway gut microbiota inflammatory mechanism reflux esophagitis
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmicb.2026.1805181/full
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