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Kynurenine Promotes Phosphate-Induced Endothelial Calcification via Endothelial-to-Mesenchymal Transition, Osteoblastic Differentiation and AhR Activation

In end-stage renal disease (ESRD), the accumulation of solutes normally excreted by the kidneys contributes to multiple complications, including vascular calcification (VC), a key factor in the heightened cardiovascular risk seen in these patients. Among VC drivers, hyperphosphatemia and the uremic...

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Principais autores: Martina Molinaro, Mario Cozzolino, Paola Ciceri
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2025-08-01
Series:Toxins
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Acceso en liña:https://www.mdpi.com/2072-6651/17/8/421
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