Kynurenine Promotes Phosphate-Induced Endothelial Calcification via Endothelial-to-Mesenchymal Transition, Osteoblastic Differentiation and AhR Activation

In end-stage renal disease (ESRD), the accumulation of solutes normally excreted by the kidneys contributes to multiple complications, including vascular calcification (VC), a key factor in the heightened cardiovascular risk seen in these patients. Among VC drivers, hyperphosphatemia and the uremic...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Martina Molinaro, Mario Cozzolino, Paola Ciceri
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-08-01
Schriftenreihe:	Toxins
Schlagworte:	kynurenine phosphate calcification endothelial cells AhR EndMT
Online-Zugang:	https://www.mdpi.com/2072-6651/17/8/421
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!