Multi-omics analysis identifies gut microbiota-glutamine axis contributing to the pathogenesis of reflux esophagitis

BackgroundReflux esophagitis (RE), a common gastroesophageal reflux disease characterized by esophageal mucosal inflammation, is closely associated with gut microbiota dysbiosis and metabolic abnormalities. The glutamine-glutamate metabolic pathway regulates inflammation and mucosal barrier function...

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Detalhes bibliográficos

Principais autores:	Yu Wu, Qi Gao, Huichao Yang, Yu Wang, Lin Lang, Bin Liu, Xiaolin Jiang, Di Li, Ximo Wang, Jing Xun, Qi Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-05-01
coleção:	Frontiers in Microbiology
Assuntos:	glutamine glutamine-glutamate metabolic pathway gut microbiota inflammatory mechanism reflux esophagitis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmicb.2026.1805181/full
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