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The association of genetic polymorphisms within the dopaminergic system with nicotine dependence: A narrative review

Nicotine, the main compound in cigarettes, leads to smoking addiction. Nicotine acts on the limbic dopamine reward loop in the midbrain by binding to nicotinic acetylcholine receptors, promoting the release of dopamine, and resulting in a rewarding effect or satisfaction. This satisfaction is essent...

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Autori principali: Jingjing Yang, Hongjuan Wang, Huan Chen, Hongwei Hou, Qingyuan Hu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-06-01
Serie:Heliyon
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2405844024091898
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