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The association of genetic polymorphisms within the dopaminergic system with nicotine dependence: A narrative review

Nicotine, the main compound in cigarettes, leads to smoking addiction. Nicotine acts on the limbic dopamine reward loop in the midbrain by binding to nicotinic acetylcholine receptors, promoting the release of dopamine, and resulting in a rewarding effect or satisfaction. This satisfaction is essent...

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Autores principales: Jingjing Yang, Hongjuan Wang, Huan Chen, Hongwei Hou, Qingyuan Hu
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2024-06-01
Colección:Heliyon
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2405844024091898
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