The unfolded protein response affects readthrough of premature termination codons
Abstract One‐third of monogenic inherited diseases result from premature termination codons (PTCs). Readthrough of in‐frame PTCs enables synthesis of full‐length functional proteins. However, extended variability in the response to readthrough treatment is found among patients, which correlates with...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Nature
2014-04-01
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| Schriftenreihe: | EMBO Molecular Medicine |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1002/emmm.201303347 |
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