Mammalian cell display with automated oligo design and library assembly allows for rapid residue level conformational epitope mapping

Abstract Precise epitope determination of therapeutic antibodies is of great value as it allows for further comprehension of mechanism of action, therapeutic responsiveness prediction, avoidance of unwanted cross reactivity, and vaccine design. The golden standard for discontinuous epitope determina...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Niklas Berndt Thalén, Maximilian Karlander, Magnus Lundqvist, Helena Persson, Camilla Hofström, S. Pauliina Turunen, Magdalena Godzwon, Anna-Luisa Volk, Magdalena Malm, Mats Ohlin, Johan Rockberg
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-07-01
Edice:	Communications Biology
On-line přístup:	https://doi.org/10.1038/s42003-024-06508-8
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!