Antibody Heavy Chain Variable Domains of Different Germline Gene Origins Diversify through Different Paths

B cells produce antibodies, key effector molecules in health and disease. They mature their properties, including their affinity for antigen, through hypermutation events; processes that involve, e.g., base substitution, codon insertion and deletion, often in association with an isotype switch. Inve...

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Xehetasun bibliografikoak

Egile Nagusiak:	Ufuk Kirik, Helena Persson, Fredrik Levander, Lennart Greiff, Mats Ohlin
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2017-11-01
Saila:	Frontiers in Immunology
Gaiak:	antibody germline gene antibody sequence somatic hypermutation immunoglobulin insertion and deletion substitution
Sarrera elektronikoa:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01433/full
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!