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Mammalian cell display with automated oligo design and library assembly allows for rapid residue level conformational epitope mapping

Abstract Precise epitope determination of therapeutic antibodies is of great value as it allows for further comprehension of mechanism of action, therapeutic responsiveness prediction, avoidance of unwanted cross reactivity, and vaccine design. The golden standard for discontinuous epitope determina...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Niklas Berndt Thalén, Maximilian Karlander, Magnus Lundqvist, Helena Persson, Camilla Hofström, S. Pauliina Turunen, Magdalena Godzwon, Anna-Luisa Volk, Magdalena Malm, Mats Ohlin, Johan Rockberg
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Portfolio 2024-07-01
Цуврал:Communications Biology
Онлайн хандалт:https://doi.org/10.1038/s42003-024-06508-8
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