Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism
Abstract Background Excitotoxicity is a mechanism of foremost importance in the selective motor neuron degeneration characteristic of motor neuron disorders. Effective therapeutic strategies are an unmet need for these disorders. Polyphenols, such as quercetin and resveratrol, are plant-derived comp...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2017-11-01
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| Seria: | Translational Neurodegeneration |
| Hasła przedmiotowe: | |
| Dostęp online: | http://link.springer.com/article/10.1186/s40035-017-0102-8 |
| Etykiety: |
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