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Histone deacetylases and their role in motor neuron degeneration

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by the progressive loss of motor neurons. The cause of this selective neuronal death is unknown, but transcriptional dysregulation is recently emerging as an important factor. The physical substrate for the regul...

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Bibliografske podrobnosti
Principais autores: Rafael eLazo-Gómez, Uri Nimrod Ramírez-Jarquín, Luis B Tovar-y-Romo, Ricardo eTapia
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013-12-01
Serija:Frontiers in Cellular Neuroscience
Teme:
Online dostop:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00243/full
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