The in vivo role of Rev1 in mutagenesis and carcinogenesis
Abstract Translesion synthesis (TLS) is an error-prone pathway required to overcome replication blockage by DNA damage. Aberrant activation of TLS has been suggested to play a role in tumorigenesis by promoting genetic mutations. However, the precise molecular mechanisms underlying TLS-mediated tumo...
Сохранить в:
| Главные авторы: | , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMC
2020-02-01
|
| Серии: | Genes and Environment |
| Предметы: | |
| Online-ссылка: | http://link.springer.com/article/10.1186/s41021-020-0148-1 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
|