The in vivo role of Rev1 in mutagenesis and carcinogenesis
Abstract Translesion synthesis (TLS) is an error-prone pathway required to overcome replication blockage by DNA damage. Aberrant activation of TLS has been suggested to play a role in tumorigenesis by promoting genetic mutations. However, the precise molecular mechanisms underlying TLS-mediated tumo...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BMC
2020-02-01
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| Collection: | Genes and Environment |
| Sujets: | |
| Accès en ligne: | http://link.springer.com/article/10.1186/s41021-020-0148-1 |
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