The in vivo role of Rev1 in mutagenesis and carcinogenesis
Abstract Translesion synthesis (TLS) is an error-prone pathway required to overcome replication blockage by DNA damage. Aberrant activation of TLS has been suggested to play a role in tumorigenesis by promoting genetic mutations. However, the precise molecular mechanisms underlying TLS-mediated tumo...
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2020-02-01
|
| Colección: | Genes and Environment |
| Materias: | |
| Acceso en línea: | http://link.springer.com/article/10.1186/s41021-020-0148-1 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|