Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2

Abstract Inhibition of Mycobacterium tuberculosis (Mtb) cell wall assembly is an established strategy for anti-TB chemotherapy. Arabinosyltransferase EmbB, which catalyzes the transfer of arabinose from the donor decaprenyl-phosphate-arabinose (DPA) to its arabinosyl acceptor is an essential enzyme...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Lu Zhang, Yao Zhao, Ruogu Gao, Jun Li, Xiuna Yang, Yan Gao, Wei Zhao, Sudagar S. Gurcha, Natacha Veerapen, Sarah M. Batt, Kajelle Kaur Besra, Wenqing Xu, Lijun Bi, Xian’en Zhang, Luke W. Guddat, Haitao Yang, Quan Wang, Gurdyal S. Besra, Zihe Rao
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2020-05-01
Serier:	Protein & Cell
Fag:	Mycobacterium tuberculosis EmbB cryo-EM ethambutol cell wall synthesis arabinoglacatan
Online adgang:	https://doi.org/10.1007/s13238-020-00726-6
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!