Sonic Hedgehog Signaling in Cranial Neural Crest Cells Regulates Microvascular Morphogenesis in Facial Development

Sonic hedgehog (Shh) pathway disruption causes craniofacial malformations including orofacial clefts (OFCs) of the lip and palate. In normal craniofacial morphogenesis, Shh signals to multipotent cranial neural crest cells (cNCCs) and was recently discovered to regulate the angiogenic transcriptome,...

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Principais autores:	Miranda R. Sun, Hannah M. Chung, Veronika Matsuk, Dustin M. Fink, Matthew J. Stebbins, Sean P. Palecek, Eric V. Shusta, Robert J. Lipinski
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2020-10-01
Serija:	Frontiers in Cell and Developmental Biology
Teme:	perivascular pericyte cranial neural crest Sonic hedgehog orofacial clefting microvascular morphogenesis
Online dostop:	https://www.frontiersin.org/article/10.3389/fcell.2020.590539/full
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