Sonic Hedgehog Signaling in Cranial Neural Crest Cells Regulates Microvascular Morphogenesis in Facial Development

Sonic hedgehog (Shh) pathway disruption causes craniofacial malformations including orofacial clefts (OFCs) of the lip and palate. In normal craniofacial morphogenesis, Shh signals to multipotent cranial neural crest cells (cNCCs) and was recently discovered to regulate the angiogenic transcriptome,...

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主要な著者:	Miranda R. Sun, Hannah M. Chung, Veronika Matsuk, Dustin M. Fink, Matthew J. Stebbins, Sean P. Palecek, Eric V. Shusta, Robert J. Lipinski
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2020-10-01
シリーズ:	Frontiers in Cell and Developmental Biology
主題:	perivascular pericyte cranial neural crest Sonic hedgehog orofacial clefting microvascular morphogenesis
オンライン･アクセス:	https://www.frontiersin.org/article/10.3389/fcell.2020.590539/full
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