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MIF functional polymorphisms are associated with acute GVHD progression and steroid-refractoriness

IntroductionApproximately 50% of allogeneic hematopoietic stem cell transplantation (HSCT) Q6 recipients develop graft versus host disease (GVHD). Glucocorticoids (GC) are the first line of treatment for both acute and chronic GVHD. Failure to respond to GC [steroid-refractory (SR)] encompasses a ve...

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Auteurs principaux: Aviran Aharon, Batia Avni, Daniel Louzoun, Shlomo Elias, Polina Stepensky, Ron Ram, Tsila Zuckerman, Roberto Meza-Romero, Arthur A. Vandenbark, Sigal Grisariu, Gil Benedek
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2025-04-01
Collection:Frontiers in Immunology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1504976/full
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