MIF functional polymorphisms are associated with acute GVHD progression and steroid-refractoriness

IntroductionApproximately 50% of allogeneic hematopoietic stem cell transplantation (HSCT) Q6 recipients develop graft versus host disease (GVHD). Glucocorticoids (GC) are the first line of treatment for both acute and chronic GVHD. Failure to respond to GC [steroid-refractory (SR)] encompasses a ve...

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Detalhes bibliográficos

Principais autores:	Aviran Aharon, Batia Avni, Daniel Louzoun, Shlomo Elias, Polina Stepensky, Ron Ram, Tsila Zuckerman, Roberto Meza-Romero, Arthur A. Vandenbark, Sigal Grisariu, Gil Benedek
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-04-01
coleção:	Frontiers in Immunology
Assuntos:	MIF acute GVHD steroid-refractory HSCT polymorphism
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1504976/full
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