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Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis

Myelination depends on timely, precise control of oligodendrocyte differentiation and myelinogenesis. Cholesterol is the most abundant component of myelin and essential for myelin membrane assembly in the central nervous system. However, the underlying mechanisms of precise control of cholesterol bi...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Xin Zhou, Seula Shin, Chenxi He, Qiang Zhang, Matthew N Rasband, Jiangong Ren, Congxin Dai, Rocío I Zorrilla-Veloz, Takashi Shingu, Liang Yuan, Yunfei Wang, Yiwen Chen, Fei Lan, Jian Hu
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2021-05-01
Schriftenreihe:eLife
Schlagworte:
Online-Zugang:https://elifesciences.org/articles/60467
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