Tissue nonspecific and intestinal alkaline phosphatase crosstalk: a missing link in hypophosphatasia pathophysiology?
Abstract Background Tissue-nonspecific alkaline phosphatase (TNSALP) and intestinal alkaline phosphatase (IAP) are functionally similar enzymes, but their relationship in hypophosphatasia (HPP) remains unexplored. This study investigated the impact of HPP—a condition caused by ALPL gene mutations th...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2026-02-01
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| Seria: | Journal of Translational Medicine |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s12967-026-07791-1 |
| Etykiety: |
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