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Prognostic relevance of TROP2 expression in patients with non-small cell lung cancer receiving immunotherapy

Abstract Trophoblast surface antigen 2 (TROP2) is strongly expressed in patients with non-small cell lung cancer (NSCLC), and its overexpression is closely associated with a worse prognosis. Recently, a novel TROP2-directed antibody–drug conjugate (ADC) has been developed, and TROP2 has been identif...

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Principais autores: Naohito Hashimoto, Shota Takei, Kyoichi Kaira, Hisao Imai, Kosuke Hashimoto, Yu Miura, Ayako Shiono, Ou Yamaguchi, Atsuto Mouri, Kunihiko Kobayashi, Mei Hamda, Hiroshi Kagamu
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2025-10-01
סדרה:Scientific Reports
נושאים:
TROP2
PD-1
CTLA4
Lung cancer
Resistance
Prognosis
גישה מקוונת:https://doi.org/10.1038/s41598-025-19362-3
תגים: הוספת תג
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