Prognostic relevance of TROP2 expression in patients with non-small cell lung cancer receiving immunotherapy

Abstract Trophoblast surface antigen 2 (TROP2) is strongly expressed in patients with non-small cell lung cancer (NSCLC), and its overexpression is closely associated with a worse prognosis. Recently, a novel TROP2-directed antibody–drug conjugate (ADC) has been developed, and TROP2 has been identif...

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Hlavní autoři:	Naohito Hashimoto, Shota Takei, Kyoichi Kaira, Hisao Imai, Kosuke Hashimoto, Yu Miura, Ayako Shiono, Ou Yamaguchi, Atsuto Mouri, Kunihiko Kobayashi, Mei Hamda, Hiroshi Kagamu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-10-01
Edice:	Scientific Reports
Témata:	TROP2 PD-1 CTLA4 Lung cancer Resistance Prognosis
On-line přístup:	https://doi.org/10.1038/s41598-025-19362-3
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