Portability of a Small-Molecule Binding Site between Disordered Proteins

Intrinsically disordered proteins (IDPs) are important in both normal and disease states. Small molecules can be targeted to disordered regions, but we currently have only a limited understanding of the nature of small-molecule binding sites in IDPs. Here, we show that a minimal small-molecule bindi...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Rajesh Jaiprashad, Sachith Roch De Silva, Lisette M. Fred Lucena, Ella Meyer, Steven J. Metallo
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	MDPI AG 2022-12-01
Σειρά:	Biomolecules
Θέματα:	intrinsically disordered proteins Myc protein-protein interaction drug targets SLiM small-molecule inhibitors
Διαθέσιμο Online:	https://www.mdpi.com/2218-273X/12/12/1887
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