Portability of a Small-Molecule Binding Site between Disordered Proteins

Intrinsically disordered proteins (IDPs) are important in both normal and disease states. Small molecules can be targeted to disordered regions, but we currently have only a limited understanding of the nature of small-molecule binding sites in IDPs. Here, we show that a minimal small-molecule bindi...

詳細記述

書誌詳細

主要な著者:	Rajesh Jaiprashad, Sachith Roch De Silva, Lisette M. Fred Lucena, Ella Meyer, Steven J. Metallo
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2022-12-01
シリーズ:	Biomolecules
主題:	intrinsically disordered proteins Myc protein-protein interaction drug targets SLiM small-molecule inhibitors
オンライン･アクセス:	https://www.mdpi.com/2218-273X/12/12/1887
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