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Association of Sonic Hedgehog with the extracellular matrix requires its zinc-coordination center

Abstract Background Sonic Hedgehog (Shh) has a catalytic cleft characteristic for zinc metallopeptidases and has significant sequence similarities with some bacterial peptidoglycan metallopeptidases defining a subgroup within the M15A family that, besides having the characteristic zinc coordination...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Carina Jägers, Henk Roelink
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2021-04-01
Rangatū:BMC Molecular and Cell Biology
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12860-021-00359-5
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